A culture of indigenous transgender women that has been part of southern Mexico’s heritage for centuries is primed for global fashion cachet thanks to one of the world’s top style magazines. For the first time in Vogue magazine’s more than 120 years of publishing, an indigenous “muxe” will appear next month on the cover of the glossy’s Mexican and British editions. Muxes, a term probably derived from the Spanish word mujer meaning woman, are indigenous transgender women who easily mix gay male and feminine identities. The cover photo features Estrella Vazquez, a tall, lanky 37-year-old indigenous Zapotec muxe wearing a traditional huipil garment with colorful flowers and holding a pink fan in one hand.