Reducing barriers to comprehensive and affirming health care for lesbian, gay, bisexual, transgender, queer and intersex (LGBTQI+) populations requires physicians to receive LGBTQI+ health content during undergraduate medical education (UME). With more than 7% of the U.S. adult population, 4% of the Canadian adult population and 20% of persons in the U.S. ages 18–25 who are LGBTQI+, there is a critical need to train health care professionals on their specific health care needs. LGBTQI+ people experience a higher prevalence of tobacco, alcohol, substance use, and mental health concerns like anxiety, depression and suicidality, as well as elevated cardiovascular disease morbidity and mortality. The Association of American Medical Colleges (AAMC) recommends core competencies regarding LGBTQI+ health-related content. Researchers at Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center (BMC), report time dedicated to these topics did increase in 2022, as compared to a study done in 2011; but they also found the breadth, efficacy, or quality of instruction continues to vary substantially.